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为明确植物乳杆菌LactiplantibacillusplantarumLPJZ-658对新生吉林花猪仔猪生长性能及肠道菌群的调控作用，选取体重相近的哺乳仔猪18头，随机分成Control组和LP组，连续灌胃63d。LP组每日灌胃1.0×1010CFU/dLPJZ-658，Control组灌胃等量生理盐水。结果显示，与Control组相比，LP组仔猪在28d和63d体重及平均日增重显著提高，料重比显著降低(P＜0.05)。16SrRNA测序结果表明，两组α多样性无显著差异，但β多样性显著分离；LP组拟杆菌门相对丰度升高，厚壁菌门降低。功能预测分析显示，LPJZ-658干预可能影响肠道菌群代谢相关通路，并降低感染性疾病相关功能的预测丰度。综上，新生阶段持续干预LPJZ-658 可促进地方种猪早期生长，并重塑肠道菌群结构与潜在功能，为地方猪早期营养调控提供理论依据。
Abstract：To clarify the regulatory effects of Lactiplantibacillus plantarum LPJZ-658 on growth performance and gut microbiota in newborn Jilin Flower piglets， 18 suckling piglets with similar initial body weight were randomly assigned to a Control group or an LP group and received intervention for 63 days. Piglets in the LP group were administered LPJZ-658 (1.0 × 1010 CFU/d) by daily oral gavage， whereas the Control group received an equal volume of physiological saline. Compared with the Control group， LP-treated piglets exhibited significantly greater body weight and average daily gain at 28 and 63 days， along with a lower feed-to-gain ratio (P < 0.05). 16S rRNA sequencing analysis revealed no significant difference in α-diversity but a clear separation in β-diversity between groups. The relative abundance of Bacteroidota increased， whereas Bacillota decreased in the LP group. Functional prediction analysis suggested that LPJZ-658 intervention may modulate metabolic pathways and reduce the predicted abundance of pathways associated with infectious diseases. In conclusion， early-life intervention with LPJZ-658 improves growth performance in local piglets and reshapes gut microbial structure and potential functions， providing a theoretical basis for early nutritional regulation in local pig breeds.
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基本信息:
中图分类号:S828.5
引用信息:
[1]陈作鹏,张加力.植物乳杆菌LPJZ-658对新生吉林花猪仔猪生长性能及肠道菌群的影响[J].经济动物学报().
基金信息:
吉林省科技攻关计划项目(20190301009NY)
2026-05-19
2026-05-19
2026-05-19