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为研究正常水貂和腹泻水貂肠道菌群差异，本试验对三组健康水貂和三组腹泻水貂的样品进行了高通量测序分析。结果显示，在门水平上与正常组相比腹泻组厚壁菌门所占比例显著增高（P<0.05），变形菌门所占比例显著减少（P<0.05）。在属水平上与腹泻组相比正常组乳酸菌属、嗜冷菌属所占比例显著增高（P<0.05）在种水平上与正常组相比腹泻组梭菌、葡萄球菌所占比例显著增高（P<0.05）解淀粉乳酸菌、乳酸球菌和乳酸杆菌所占比例显著减少（P<0.05）。由此可见正常和腹泻水貂粪便中的菌群结构有着明显差异，水貂肠道菌群中梭菌、葡萄球菌等条件致病菌的占比和相对丰度的增加；解淀粉乳酸菌、乳酸球菌和乳酸杆菌等益生菌的占比降低是导致水貂腹泻的原因之一。
Abstract：Diarrhea To investigate the differences in the intestinal microbiota between normal and diarrheic mink， fecal samples from three groups of healthy mink and three groups of diarrheic mink were analyzed by high-throughput sequencing in this study. The results showed that， at the phylum level， the proportion of Firmicutes was significantly increased (P<0.05)， while the proportion of Proteobacteria was significantly decreased (P<0.05) in the diarrheic group compared to the normal group. At the genus level， the proportions of Lactobacillus and Psychrobacter were significantly higher (P<0.05) in the normal group compared to the diarrheic group. At the species level， the proportions of Clostridium and Staphylococcus were significantly increased (P<0.05)， whereas the proportions of Lactobacillus amylovorus， Lactococcus， and Lactobacillus were significantly decreased (P<0.05) in the diarrheic group compared to the normal group. These findings indicate a distinct difference in the microbial community structure between the feces of normal and diarrheic mink. The increased proportion and relative abundance of opportunistic pathogens such as Clostridium and Staphylococcus， along with the decreased proportion of beneficial bacteria such as Lactobacillus amylovorus， Lactococcus， and Lactobacillus in the intestinal microbiota， may be one of the contributing factors to diarrhea in mink.
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基本信息:
中图分类号:S858.92
引用信息:
[1]赵鑫,戚少华,于德涛,等.基于高通量测序正常和腹泻水貂肠道菌群差异性分析[J].经济动物学报().
基金信息:
山东省现代农业产业技术体系建设专项资助（SDARS-21-13）
2026-03-12
2026-03-12
2026-03-12